With some terrific road trip options in the surrounding area, renting a car makes sense. Without one, it’d be much harder to explore everything that Cape Girardeau, 40 miles away, has to offer. Explore the area beginning with Isle Casino Cape Girardeau, Lazy L Safari Park and Cape Girardeau Conservation Nature Center. Don’t skip Metropolis either! Just 50 miles away, Harrah’s Metropolis, Superman Statue and Fort Massac State Park are essential stops here.