Isle of Palms. So much to see and do, so little time. Before you set off in your rental car and discover the place, we’ll get you up to speed on some important info.You’ll discover differences in culture and customs throughout United States of America, Isle of Palms is no exception.If you want to get some local advice on things to check out, you won’t have any issues. The island is home to around 4,100 friendly people who’ll be happy to guide you in the right direction.