With some awesome road trip options in the surrounding area, renting a car makes good sense. Without one, it wouldn’t be half as easy to enjoy all that Greenville, 35 miles away, has to offer. Among your first stops here should be Trop Casino Greenville, Harlow’s Casino and Lake Ferguson. The locals will also likely point you toward Clarksdale, 35 miles away. If you only have time for one thing here, make sure it’s Delta Blues Museum. (But we’d also recommend Red’s Lounge and New Roxy.)